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Big Pharma: The Game: The Guide. Welcome & Intro to Game Basics Welcome message & Basic description of game. Hello and welcome to my latest guide. This guide will cover the PC game 'Big Pharma', an indie puzzle/simulation/tycoon game by Twice Circled, published by Positech Games.

Big Pharma is a simulation game, where one builds a drug factory. The player is at the forefront of a pharmaceutical company, an economic puzzle where balancing the properties of medicines and organizing the factory is the main mission. The focus of the game is solely on the production of medicines and the salvation of the world of various diseases. In order to make the medicines at all, first you need to get the ingredients that you will be processing until you finally make tablets, creams and the like.

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Each ingredient has one positive effect and one to three side effects that have a negative effect on the quality of the obtained drug. In order to activate the positive effect of the substance, it is necessary to bring it to a certain concentration as indicated in its description (randomly each time). The main task is to balance the positive and negative properties of the drugs through changing their concentration and mixing with other elements.
When you put the Lek on the market, it will be assigned a rating under the well-known system of F-S where the “F” mark is catastrophically bad and the “S” rating for the best possible drug. Logically, the better you get, the better you will be earning from selling that bet. Your empire will start modestly, from a very small building where you have a place to produce just one drug.

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Once you have chosen a substance for the limb, you will be able to move the moving bars through which you will transport your future liver to machines where you increase or decrease the concentration of the drug until you get the desired effect. Like your factory, the production line will be simple with several machines. Headache, on the other hand, will make proper use of the space available to you.
The machines are large and have clearly marked locations where they can be linked to production lines, so spatial planning is often the highest priority. Do a bad schedule of machines cost you a thousand dollars of cost until you build it again and optimally adjust it. The very process of creating another is pure handling of numbers, constantly calculating and reducing the production line so that as few machines produce the desired lime.

Over time, you will explore more advanced machines that will work with a number of cheaper or even mix ingredients to eliminate unwanted (bad) effects of the medication. At the beginning of each of the scenarios available, there are very few ingredients for the medicines and new ones you have to discover by engaging researchers. One of the tabs shows current demand for medicines and widespread symptoms so you can plan on what ingredients to buy.
In each of the scenarios the effects of substances, medicines and market demand are randomly generated, so the value of re-playing is large, while reducing the chance of players learning the game and completing their mission by automation. Your initial factory, ie your scheme, and the walls on which you are importing / selling are randomly generated.

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The greater the number of scenarios you set for the opponent AI routine, with the same initial resources and tasks. AI is solid and has several variants of behavior, so one of them is the evil corporation that will sell huge quantities of inferior quality medicines to tame the market before your potentially better medicines reach customers.
After a while you will not be able to sell the same drug, you will have to produce a brand new drug, in addition to minus, and reorganize your machine in the factory. BigPharma is a game that you simply can not get angry. Constantly positive tone that draws every bit of play, pastel colors and unmistakable music round off the generally relaxed experience that you will have.

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Big Pharma is a puzzle game that you play lightly with coffee or tea, at least until you look at the clock and see that the odds of one or two turn into a multi-hour game.

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